6. Diazepam(valium) 사용군은 치료효과에 있어서 diazepam을 사용하지 않았던 군에 비해 통계적으로 유의한 차이는 없었으나 임상적으로는 차이가 있어서 diazepam사용군은 46례중 17례(0.370), diazepam을 사용하지 않았던 군은 58례중 16례(0.276)가 치유되었다.
Clinical Review of Neonatal Tetanus(104 cases) (1960-1975)
Suk Kyu Cha
Department of Medical Science, The Graduate School Yonsei University
(Directed by Prof. Duk Jin Yun, M.D.)
Neonatal tetanus is still one of the serious problems in Korea because of its
relatively high incidence. The incidence of neonatal tetanus has not changed during
the past 16 years, and the motality rate is still high even with newer methods of
treatment.
This paper reviewed the epidemiological aspects and clinical courses of 104 cases
of neonatal tetanus treated during 1960 to 1975 at Dept. of Pediatrics, Severance
Hospital.
(1) Of 104 cases, 92 cases(88%) delivered in contaminated environments. Umblical
cord contamination by unsterile instrument was frequent source of infection.
(2) The number of boys was greater than the number of girls, with male : female
ratio of 3.7:1
(3) The most cases appeared in summer.
(4) The incubation period was usually 5 to 6 days.
(5) The clinical feature may be summerized as follows : poor sucking, convulsion,
trismus and rigidity.
(6) Despite treatment 71 cases(68%) died. Motality did not vary significantly
with different dosages of tetanus antitoxin but with diazepem(Valium). The most
fatal cases associated with short incubation period high fever on admission.
[영문]
Neonatal tetanus is still one of the serious problems in Korea because of its relatively high incidence. The incidence of neonatal tetanus has not changed during the past 16 years, and the motality rate is still high even with newer methods of
treatment.
This paper reviewed the epidemiological aspects and clinical courses of 104 cases of neonatal tetanus treated during 1960 to 1975 at Dept. of Pediatrics, Severance Hospital.
(1) Of 104 cases, 92 cases(88%) delivered in contaminated environments. Umblical cord contamination by unsterile instrument was frequent source of infection.
(2) The number of boys was greater than the number of girls, with male : female ratio of 3.7:1
(3) The most cases appeared in summer.
(4) The incubation period was usually 5 to 6 days.
(5) The clinical feature may be summerized as follows : poor sucking, convulsion, trismus and rigidity.
(6) Despite treatment 71 cases(68%) died. Motality did not vary significantly with different dosages of tetanus antitoxin but with diazepem(Valium). The most fatal cases associated with short incubation period high fever on admission.