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Zea Mays L. 불검화 정량추출물의 중등도 치주염의 치료효과에 관한 임상적 연구

Other Titles
 (The) clinical study of therapeutic effect of the unsaponifiable standard extract of Zea Mays L. on moderate periodontitis 
Issue Date
1991
Description
치의학과/석사
Abstract
[한글] Zea Mays L. 불검화 정량추출물이 중등도 치주염에서 단독투여 또는 구강위생교육, 치석제거술, 치은연하 소파술, 치은박리수술과 병행투여시의 치료 효과를 연구하기 위하여 62명의 환자에서 부착상실이 4∼5mm인 694부위를 대상으로 초진시 치주임상지수(치주낭 깊이, 부착상실, 출혈지수, 치태지수)를 측정한 후 대조군에는 위약을 투여하고 실험군에는 ZML 35mg을 투여하면서 1군은 무처치, 2군은 구강위생교육, 3군은 치석제거술, 4군은 치은연하소파술, 5군은 치은박리수술후 4, 8, 12, 16주에 임상지수들을 재측정하고 이를 관찰분석하여 다음과 같은 결론을 얻었다. 1. 1군(무처치군)에서 치주낭 깊이와 부착상실은 실험군, 대조군 모두 초진시에 비해 유의성있게 감소하였으며(P<0.05), 실험군과 대조군 사이의 유의성있는 차이는 없었다. 2. 2군(구강위생교육군)에서 치주낭 깊이와 치태지수는 대조군에 비해 실험군이 유의성 있게 감소하였으며(P<0.05) 부착상실, 출혈지수는 실험군과 대조군 모두 유의성있게 감소하였으나, 실험군과 대조군 사이의 유의성있는 차이는 없었다. 3. 3군(치석제거술군)에서는 치태지수의 경우 실험군이 대조군에 비해 각 주에서 유의성있게 감소하였으며(P<0.05) 치주낭 깊이, 출혈지수, 부착상실은 실험군과 대조군 모두 유의성있게 감소하였으나(P<0.05), 실험군과 대조군 사이의 유의성있는 차이는 없었다. 4. 4군(치은연하소파술군)에서 치주낭 깊이, 부착상실은 대조군과 실험군 모두 각주에서 초진시에 비해 유의성있게 감소하였으나(P<7.05), 대조군과 실험군 사이의 유의성있는 차이는 없었다. 5. 5군(치은박리수술군)에서 실험군은 초진시에 비해 치주낭 깊이, 부착상실, 출혈지수, 치태지수 모두 유의성있게 감소하였지만(P<0.75), 실험군과 대조군 사이의 유의성있는 차이는 없었다.
[영문] The purpose of this study was to evaluate the therapeutic effect of unsaponifiable standard extract of Zea Mays L. with various periodontal treatment on moderate periodontitis. This study was carried 7ut on 694 site which had loss of attachment of 4∼5mm among 62 individuals. The subjects were divided randomly into 5 treatment groups. 5 treatment groups were consisted of no treatment, oral hygiene instruction, scaling subgingival curettage and flap operation group. The administration was Zea Mays L. 35mg for experimental group, placebo for control group. Probing depth, loss of attachment, bleeding index, plaque index were recorded at baseline and 4, 8, 12, 16 weeks after earth treatment. The results were as follows. 1. For group 1(no treatment), both experimental and control group were statistically significantly reduced in probing depth and loss of attachment(P<0.05) but there was no statistically significant difference between experimental and control group. 2. For group 2(oral hygiene instruction), the experimental group was more statistically significantly reduced than control group in probing depth and plaque index. In loss of attachment and bleeding index both experimental and control group were reduced significantly but there was no statistically significant difference between experimental and control group. 3. Fer group 3(scaling), the experimental group was mare significantly reduced than control group in plaque index In probing depth, bleeding index and loss of attachment both experimental and control group were significantly reduced but there was no statistically significant difference between experimental and control group. 4. Fer group 4(subgingival curettage), both experimental and control group were significantly reduced but there was no significant difference between experimental and control group in probing depth and loss of attachment. 5. For group 5(flap operation), both experimental and control group were significantly reduced but there was no statistically significant difference between experimental and control group in probing depth, loss of attachment, bleeding index, plaque index.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/116788
Appears in Collections:
2. 학위논문 > 2. College of Dentistry (치과대학) > 석사
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