Cited 0 times in

진행된 치주염에서 Zea Mays L. 불검화 정량추출물의 치료효과에 대한 임상적 연구

Other Titles
 Clinical study of standard extract of the unsaponifiable fraction of Zea Mays L. on therapeutic effect in advanced periodontitis 
Issue Date
1992
Description
치의학과/석사
Abstract
[한글] 진행된 치주염에서 Zea Mays L.의 불검화 정량추출물을 단독투여, 혹은 구강위생교육, 치석제거슬, 치은연하소파술 및 치은박리수술 등과 병행투여시의 효과를 알아보기 위하여 53명의 환자에서 부착상실이 6mm 이상인 671개의 진행된 치주염 부위의 초진시 치주임상지수(치주낭 깊이, 부착상실, 출혈지수, 치태지수)를 측정한 후 실험군에는 ZML, 대조군에는 위약을 투여하면서 1군은 무처치, 2군은 구강위생교육, 3군은 치석제거술, 4군은 치은연하소파술, 5군은 치은박리수술을 시행한 후 4주간격으로 16주간 임상지수들을 재측정 하고 이를 관찰, 분석하여 다음과 같은 결론을 얻었다. 1.1군(무처치군)에서 치주낭 깊이와 부착상실은 실험군과 대조군 모두에서 유의성있는 감소를 보였으며(P<0.05), 실험군과 대조군 사이의 비교에는 유의차가 없었다. 2. 2군(구강위생교육 시행군)에서 치주낭깊이, 부착상실, 출혈지수, 치태지수가 4, 8, 12, 16주에서 실험군이 대조군에 비해 더 유의성있는 감소를 보였다(P<0.05). 3. 3군(치석제거술 시행군)에서 치주낭깊이, 부착상실, 출혈지수, 치태지수가 실험군과 대조군모두에서 유의성있는 감소를 보였으며(P<0.05), 실험군에서 치주낭깊이와 부착상실이 12주에서, 그리고 치태지수가 4, 8, 12주에서 대조군에 비해 더 유의성있는 감소를 보였다(P<0.05). 4. 4군(치은연하소파술 시행군)에서 치주낭깊이, 부착상실, 출혈지수가 실험군과 대조군 모두에서 유의성있는 감소를 보였으며(P<0.05), 실험군과 대조군의 비교에서는 큰 차이가 없었다. 5. 5군(치은박리수술 시행군)에서 치주낭깊이, 부착상실, 출혈지수, 치태지수가 실험군과 대조군 모두에서 유의성있는 감소를 보였으며(P<0.05), 실험군에서 부착상실이 4, 8주에서 대조군에 비해 더 유의성있는 감소를 보였다(P<0.05).
[영문] The purpose of this study was to evaluate the therapeutic effect of standard extract of the unsaponifiable fraction of Zea Mays L. when administered alone, or combined with oral hygiene instruction, scaling subgingival curettage, and flap operation in advanced periodontits. This study was carried out on 671 advanced periodontitis sites which had loss of attachment more than 6mm among 53 patients. Clinical parameters such as probing depth, loss of attachment, bleeding index, and plaque index were recorded on initial examination. During administration of standard extract of the unsaponiflable fraction of Zea Mays L. to experimental group and placebo to control group, 5 types of therapy were performed : (1) no treatment, (2) oral hygiene instruction, (3) scaling, (4) subgingival curettage, and (5) flap operation. Clinical parameters were recorded on 4,8,12,16 weeks after treatments, and all data were analysed statistically. The results were as follows. 1. For group 1 (no treatment), there were significant reductions of probing depth and loss of attachment in both experimental and control group, (P<0.05) and there was no significant difference between experimental and control group. 2. For group 2 (oral hygiene instruction), the reduction of all clinical parameters on 4, 8, 12, 16weeks in experimental group is significantly different compared to control group(P<0.05). 3. For group 3 (sealing), there were significant reductions of all clinical parameters in both experimental and control group(P<0.05). The reduction of probing depth and loss of attachment on 12weeks and plague index on 4,8,12 weeks in experimental group is significantly different compared to Control group(P<0.05). 4. For group 4 (subgingival curettage), there were significant reductions of probing depth, loss of attachment, and bleeding index in both experimental and control group(P<0.05), and there was no significant difference between experimental and control group. 5. For group 5 (flap operation), there were significant reductions of all clinical parameters in both experimental and control group(P<0.75). The reduction of loss of attachment on 4,8 weeks in experimental group is signifcantly different compared to control group(P<0.05).
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/116289
Appears in Collections:
2. 학위논문 > 2. College of Dentistry (치과대학) > 석사
사서에게 알리기
  feedback
Fulltext
교내이용자 서비스로 제공됩니다.
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse