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한국인의 설종양(舌腫瘍)에 관한 임상 및 병리조직학적 연구

Other Titles
 Clinical and histopathological studies on the tongue tumors in Koreans 
Authors
 박형식 
Issue Date
1978
Description
치의학과/석사
Abstract
[한글]

저자는 한국인에 발행한 설종양(舌腫瘍) 132예를 임상 및 병리조직학적으로 연구하였다. 연구재료는 1964년 1월부터 1976년 12월까지 만 13년간 연세대학교 의과대학 병리학교실에서 생검된 한국인의 검색표본중 설종양으로 진단된 예를 대상으로 하였고 이들을 통법에 의해 5∼6μ의 두께로 절편하여 H-E염색후 관학현미경상에서 재검경하였으며, 임상기록을 검토하고 이들을 종합하여 다음과 같은 결론을 얻었다.

1. 총 증례 132예중 양성종양이 62예(47%) 악성종양이 70예(53%) 였다.

2. 양성종약 62예중에는 유두종 22예(35.5%) 용종 16예(25.9%) 혈관종 15예(24.1%) 신경초종 4예(6.5%) 지방종과 임파관종이 각기 2예(3.2%)씩 점액연골종이 1예(1.6%)의 순이었으며, 이중 혈관종에서는 해면상혈관종이 가장 많았다(73.3%).

3. 악성종양 70예중에는 암종이 67예(95.7%) 육종이 3예(4.3%) 였으며, 이중 상피암종이 59예(84.4%)로 가장 많았고 퇴행성암종 혈관육종 세망세포육종 악성혈관내피종도 각 1예(1.4%)씩이었으며 백반증도 3예(4.3%)나 되었다.

상피암종 59예중에는 고분화군이 35예(59.3%) 중등도분화군이 13예(22.0%) 미분화군이 11예(18.7%)의 순이었다.

4. 성별은 양성종양이 남자 30예(48.4%) 여자 32예(51.6%)로 비슷하였으나 악성종양에서는 2.5:1로 남자에 빈발하였고, 년령은 양성종양이 전연령층에 비교적 균등한 빈도를 보였으나 악성종양은 40∼60대군(80%)에 빈발하였으며, 평균년령은 양성종양이 37.8세 악

성종양이 53.6세였다.

5. 주소는 양성종양이 62예중 가시종괴 45예(72.6%) 동통 및 불편감 9예(14.6%) 이물감 3예(4.8%)등의 순이었으나 악성종양은 70예중 가시종괴 29예(41.4%) 궤양 21예(30.0%) 동통 및 불편감 11예(15.7%) 등의 순이었고, 병력기간은 1년이하군이 양성종양 40예(64.5%), 악성종양 57예(81.4%)였으며 5년이상군은 양성종양이 12예(19.4%) 약성종양이 5예(7.2%)였다. 이중 상피암종의 주소는 분화도와는 무관하였으나 병력기간은 고분화군일수록 길었다.

6. 부위별 발생빈도는 양성종양이 62예중 전2/3부위가 29예(46.9%) 배면 19예(30.6%) 후1/3부위 8예(12.9%)등을 보였고 악성종양은 70예중 전2/3부위가 41예(58.6%) 후1/3부위가 16예(22.9%) 배면 4예(5.7%)등의 순이었다.

7. 병소의 크기는 0∼2cm, 군이 양성종양 41예(66.1%), 악성종양 38예(54.3%)로 가장 많았으며 4cm, 이상군은 양성종양 3예(4.9%) 약성종양 8예(11.4%)로 가장 적었다.

8. 악성종양중 TNM분류가 가능했던 36예에서 StageⅡ이 12예(33.3%) StageⅠ이 11예(30.6%) StageⅣ가 10예(27.8%) StageⅡ가 3예(8.3%)였고, 악성종양의 전이율은 발생부위가 후방부에 위치할수록, 또한 크기가 클수록 전이되는 비율이 높았다.







[영문]

The author has studied clinically and histopathologically on the 132 cases of tongue tumors in Koreans during the period of Jan., 1964 to Dec., 1975.

Those materials were obtained from the Department of Pathology, College of Medicine of Yonsei University.

The results of these studies are as follows;

1. Among the 132 cases of tongue tumor, benign tumors were 62 cases(47%) and malignant tumors were 70 cases(53%).

2. In the 62 cases of benign tumor of the tongue, the highest incidence was 22 cases(35.5%) of papilloma, and the lowest was one(1.6%) of Myxochondroma.

3. In the 70 cases of malignant tumor of the tongue, carcinomas were 67 cases(95.7%) and sarcomas were 3 cases(4.3%). Of these, the highest incidence was 59 cases(84.4%) of epidermoid carcinoma, and the lowest was each one(1.4%) of anaplastic carcinoma, angiosarcoma, reticulum cell sarcoma and malignant

hemangioendothelioma. In 59 cases of epidermoid carcinoma well-differentiated group was 35 cases(59.3%), moderately well-differentiated group was 13 cases(22.0%) and poorly-differentiated group was 11 cases(18.7%).

4. The sexual incidence was relatively same in benign tumor, but male was predominant in malignant tumor(2.5:1).

As to the age distribution of tongue tumor, each decade group showed relatively same distribution in benign tumor, but 40-60 decade group showed the highest incidence(56 cases or 80%) in malignant tumor. Average age for tongue tumor was 37.8 years in benign tumor and 53.6 years in malignant tumor.

5. The most common complaint of benign tumor was visible mass(45 cases or 72.6%), followed by pain and discomfort(9 cases or 14.6%) and foreign body sensation(3 cases or 4.8%), etc.. Malignant tumor showed 29 cases(41.4%) of visible mass, 21 cases (30.0%) of ulceration and 11 cases(15.7%) of pain & discomfort, etc..

6. The most common site of origin of benign tumor was anterior 23 portion(29 cases or 46.9%), followed by dorsum(19 cases or 30.6%) and posterior 1/3 portion(8 cases or 12.9%) etc.. Malignant tumor showed 41 cases(58.6%) of anterior 2/3 portion, 16 cases(22.9%) of posterior 1/3 portion and 4 cases(5.7%) of dorsum, etc..

7. The size of lesion was 2cm. or less in most cases(66.1% in benign tumor and 54.3% in malignant tumor).

8. Among the 36 cases of malignant tumor which were able to determine TNM classification, the highest incidence was 12 cases(33.3%) of stage Ⅲ, and the lowest was 3 cases(8.3%) of stage Ⅱ.

The more posterior lesion was and the more large lesion was, the more its metastatic rate was increased.
Full Text
https://ymlib.yonsei.ac.kr/catalog/search/book-detail/?cid=CAT000000008207
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Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Advanced General Dentistry (통합치의학과) > 2. Thesis
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/115950
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