5. 임파종중에서는 임파구성임파종이 47%로 가장 많았고 조직구성임파종이 25%였으며 Hodgkin's lymphoma는 15.4%로 비교적 적었다.
6. 외국의 보고에 비하여 임파종의 빈도가 높았던 반면 중추신경계종양의 빈도는 낮았다.
7. 교감신경조직종양중에는 신경아세포종(83.3%), 중추신경계종양 중에는 수아세포종(63%), 골종양중에는 골육종(66.7%)이 가장 많았다.
[영문]
Since the antibiotic era cancer is the second most common cause of death in children preceded only by death due to accident in the developed countries.
Cummulative epidemiologic studies have shown that there were geographical and racial variations in the incidence of malignant childhood cancer according to the histologic type. Furthermore malignant tumors arising in pediatric age is known to differ from those of adult.
In the present study, the author analized 277 malignant neoplasms. The materials were those obtained by biopsy or surgical excision in Yonsei University during the period from 1975 to 1981. Re-evaluation with histological confirmation was made, followed by study on the type and frequency of the pediatric cancer among Korean and on some clinical correlations.
The results were as follows:
1. The annual ratios of malignant tumors of infancy and childhood to total pediatric admission were net increased from 1975 to 1981, being 1.21-1.72%.
2. In general, male was the victim of cancer 1.45 times more frequently than female. And nearly half of the pediatric malignancy(49.8%) was under the age of 5.
3. Of the 277 malignancies, leukemia comprised 35%, which was followed, in decreasing order of frequency, by lymphoma(11.5%), tumors of the sympathetic nerve system(10.8%), tumors of the central nervous system(6.9%) and carcinomas(6.9%). In particular, carcinomas of varying visceral organs or tissues ranked the second in female preceded only by leukemia and followed by tumors of the sympathetic nerve system(9.7%), bone tumors(8.8%) and soft tissue tumors(8.0%).
4. Among the 97 cases of leukemia 97.7% was acuter and acute lymphocytic leukemia comprised 74%, acute myelogenous leukemia being only 13.3%.
5. With respect to the malignant lymphoma, lymphocytic lymphoma was the most common type followed by histiocytic lymphoma. Hodgkin's disease was found in only 15.4% of all leukemia.
6. Lymphoma appeared more frequent in Korea than in abroad, and in tumors of central nervous system the reverse was true.
7. Among the tumors arising in sympathetic nerve system, 83% was neuroblastoma.
Medulloblastoma and osteosarcoma were the commonest tumors of central nervous system and bone, being 63.0 and 66.7% respectively.