[영문]The importance of serological tests in diagnosis of syphilis is reflected by the following facts: Syphilis may similate many diseases thus rendering an acurate diagnosis difficult on the basis of clinical sings and symptoms alone: Primary, secondary, or tertiary manifestations may not develop; and latenoy may occur during the course of the disease. Furthermore, the present day, the clinical syphilis patients are very rare due to indiscriminate use of antibiotics.
In spite of some data of syphilis incidence in korea by several investigators the data obtained only by non-treponemal tests in which so called biological false positive reactions are high, a true picture of syphilis incidence in Korea has not yet been obtained.
The purpose of this report is to support the syphilis incidence of former reports by non-treponemal tests (VDRL slide flocculation test and Kolmer CF test), and RPCF test which is highly sensitive and specific for the diagnosis of syphilis,
confirmed by various investigators, and to develop a practical test plan for the serologio diagnosis of syphilis in Korea, by comparing the non-treponemal tests with the RPCF test.
The non-treponemal tests (VDRL slide flocculation test and Kolmer CF test), and RPCF test were performed for the prostitutes for foreigners, 910, the local prostitutes in Seoul, 168, the leprosy patients of Special Skin Clinic, 188, and the selected athletes for the international athletics, 337, and the results were obtained as followings:
1. VDRL slide flocculation test: 16.9% in the prostitutes for the foreigners, 10.7% in the local prostitutes in Seoul, 24.5% in the leprosy patients of Special Skin Clinie, and 7.4% in the athletes were reactive to the VDRL slide flocculation test.
2. Kolmer CF test: 20.9% in the prostitutes for the foreigners, 16.1% in the local prostitutes in Seoul, 27.1% in the leprosy patients, and 9.2% in the Kolmer CF test.
3. RPCF test: 4.7% in the prostitutes for foreigners, 5.4% in the local prostitutes in Seoul, 12.2% in the leprosy patients, and 1.5% in the athletes were reactive to the RPCF test.
4. By the basis of the results in this experiments, a practical test plan is presented, This test plan is designed to help the private physician making an acurate diagnosis of syphilis, and on the basis of the results of VDRL side flocculation test, Kolmer CF test, and RPCF test.