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한국인의 경동맥 내중막 두께 정상치와 죽상경화증 위험인자와의 상관관계

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dc.contributor.author안철우-
dc.date.accessioned2015-07-15T17:03:56Z-
dc.date.available2015-07-15T17:03:56Z-
dc.date.issued2003-
dc.identifier.issn1738-9364-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/114156-
dc.description.abstractBACKGROUND: Atherosclerosis is an important cause of cardiovascular and cerebrovascular diseases, which are the major cause of death in middle-aged and older adults. However atherosclerotic lesions are not easily detected before they cause symptoms and signs which means that early detection is important. In Korea it has been reported that the carotid artery intima-media thickness (IMT) correlates well with the atherosclerotic risk factors in type 2 diabetes mellitus, but there is little data available on the carotid artery IMT in healthy subjects. Therefore, the aims of this study were to determine the reference values of the carotid artery IMT in healthy subjects and to investigate the associations of the carotid artery IMT with the atherosclerotic risk factors. METHODS: Ultrasound high-resolution B-mode imaging of the carotid arteries was conducted in 757 healthy subjects (385 men, 372 women) in order to determine the mean and maximal carotid artery IMT and the presence of carotid artery atherosclerotic plaques. RESULTS: The mean carotid artery IMT values with respect to gender were 0.69+/-0.18 mm in men and 0.67+/-0.16 mm in women (NS). The mean carotid artery IMT values with respect to age in men and women were 0.57+/-0.09 mm vs 0.57+/-0.10 mm in those aged 30 to 39, 0.61+/-0.11 mm vs 0.60+/-0.10 mm in those aged 40 to 49, 0.72+/-0.21 mm vs 0.67+/-0.12 mm in those aged 50 to 59, 0.77+/-0.15 mm vs 0.71+/-0.13 mm in those aged 60 to 69 and 0.88+/-0.18 mm vs 0.76+/-0.20 mm in those aged 70 to 79, respectively. The mean carotid artery IMT was significantly greater with increasing age (p < 0.001), particularly between those aged 40 to 49 and 50 to 59 (p < 0.001). The maximal carotid artery IMT values for men (0.72+/-0.22 mm) were significantly greater than women (0.69+/-0.15 mm). The maximal carotid artery IMT values with respect to age in men and women were 0.60+/-0.10 mm vs 0.61+/-0.12 mm in those aged 30 to 39, 0.65+/-0.11 mm vs 0.64+/-0.11 mm in those aged 40 to 49, 0.79+/-0.29 mm vs 0.71+/-0.14 mm in those aged 50 to 59, 0.83+/-0.20 mm vs 0.77+/-0.18 mm in those aged 60 to 69 and 0.97+/-0.29 mm vs 0.80+/-0.22 mm in those aged 70 to 79. The mean carotid artery IMT was significantly greater with increasing age (p < 0.001), particularly between those aged 40 to 49 and 50 to 59 (p < 0.001). Age, systolic and diastolic BP, body mass index, waist/hip ratio, totai cholesterol, LDL cholesterol correlated with the mean and maximal carotid artery IMT, and smoking, serum glucose, triglyceride, and HDL cholesterol levels were not correlated with the mean and maximal carotid artery IMT. Being male correlated with the maximal carotid artery IMT, but not correlated with the mean carotid artery IMT. CONCLUSION: This study suggested reference values for the mean and maximal carotid artery IMT in healthy subjects, which can be an index for the carotid artery IMT of Koreans. Furthermore, there were significant correlations between the carotid artery IMT and the atherosclerotic risk factors in healthy subjects.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.relation.isPartOfKorean Journal of Medicine (대한내과학회지)-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAtherosclerosis-
dc.subject.MESHCarotid artery intima-media thickness (IMT)-
dc.subject.MESHReference values-
dc.subject.MESHAtherosclerotic risk factors-
dc.title한국인의 경동맥 내중막 두께 정상치와 죽상경화증 위험인자와의 상관관계-
dc.title.alternativeReference values of carotid artery intima-media thickness and association with atherosclerotic risk factors in healthy subjects in Korea-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthor조유리-
dc.contributor.googleauthor김대중-
dc.contributor.googleauthor허갑범-
dc.contributor.googleauthor이현철-
dc.contributor.googleauthor김경래-
dc.contributor.googleauthor임승길-
dc.contributor.googleauthor차봉수-
dc.contributor.googleauthor안철우-
dc.contributor.googleauthor김형진-
dc.contributor.googleauthor김수경-
dc.contributor.googleauthor최성희-
dc.contributor.googleauthor김하동-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02270-
dc.relation.journalcodeJ02060-
dc.subject.keywordAtherosclerosis-
dc.subject.keywordCarotid artery intima-media thickness (IMT)-
dc.subject.keywordReference values-
dc.subject.keywordAtherosclerotic risk factors-
dc.contributor.alternativeNameAhn, Chul Woo-
dc.contributor.affiliatedAuthorAhn, Chul Woo-
dc.rights.accessRightsfree-
dc.citation.volume64-
dc.citation.number3-
dc.citation.startPage275-
dc.citation.endPage283-
dc.identifier.bibliographicCitationKorean Journal of Medicine (대한내과학회지), Vol.64(3) : 275-283, 2003-
dc.identifier.rimsid52033-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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