Cited 0 times in
Correlation between midthigh low-density muscle and insulin resistance in obese nondiabetic patients in Korea
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 안철우 | - |
dc.contributor.author | 차봉수 | - |
dc.date.accessioned | 2015-07-15T16:42:52Z | - |
dc.date.available | 2015-07-15T16:42:52Z | - |
dc.date.issued | 2003 | - |
dc.identifier.issn | 0149-5992 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/113451 | - |
dc.description.abstract | OBJECTIVE: We investigated the link between lipid-rich skeletal muscle, namely low-density muscle, and insulin resistance in Korea. RESEARCH DESIGN AND METHODS: Abdominal adipose tissue areas and midthigh skeletal muscle areas of 75 obese nondiabetic subjects (23 men, 52 women; mean age +/- SD, 41.9 +/- 14.1 years) were measured by computed tomography (CT). The midthigh skeletal muscle areas were subdivided into low-density muscle (0 to +30 Hounsfield units) and normal-density muscle (+31 to +100 Hounsfield units). The homeostasis model assessment (HOMA) score was calculated to assess whole-body insulin sensitivity. RESULTS: The abdominal visceral fat area and the midthigh low-density muscle area were found to be well correlated with the HOMA score (r = 0.471, P < 0.01 and r = 0.513, P < 0.01, respectively). The correlation between low-density muscle area and insulin resistance persisted after adjusting for BMI or total body fat mass (r = 0.451, P < 0.01 and r = 0.522, P < 0.01, respectively) and even after adjusting for abdominal visceral fat area (r = 0.399, P < 0.01). CONCLUSIONS: The midthigh low-density muscle area seems to be a reliable determinant of insulin resistance in Korean obese nondiabetic patients. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1825~1830 | - |
dc.relation.isPartOf | DIABETES CARE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Abdomen | - |
dc.subject.MESH | Adipose Tissue/anatomy & histology* | - |
dc.subject.MESH | Adipose Tissue/diagnostic imaging | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Fasting | - |
dc.subject.MESH | Fatty Acids, Nonesterified/blood | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Glucose Intolerance/blood | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Insulin Resistance/physiology* | - |
dc.subject.MESH | Korea | - |
dc.subject.MESH | Life Style | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Muscle, Skeletal/anatomy & histology* | - |
dc.subject.MESH | Muscle, Skeletal/diagnostic imaging | - |
dc.subject.MESH | Obesity/physiopathology* | - |
dc.subject.MESH | Postmenopause | - |
dc.subject.MESH | Premenopause | - |
dc.subject.MESH | Regression Analysis | - |
dc.subject.MESH | Skin | - |
dc.subject.MESH | Thigh | - |
dc.subject.MESH | Tomography, X-Ray Computed | - |
dc.title | Correlation between midthigh low-density muscle and insulin resistance in obese nondiabetic patients in Korea | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Dolmi Kim | - |
dc.contributor.googleauthor | Suyoun Nam | - |
dc.contributor.googleauthor | Kapbum Huh | - |
dc.contributor.googleauthor | Hyunchul Lee | - |
dc.contributor.googleauthor | Kyungrae Kim | - |
dc.contributor.googleauthor | Sungkil Lim | - |
dc.contributor.googleauthor | Bongsoo Cha | - |
dc.contributor.googleauthor | Junuh Kim | - |
dc.contributor.googleauthor | Soojee Yoon | - |
dc.contributor.googleauthor | Kyungwook Kim | - |
dc.contributor.googleauthor | Chulwoo Ahn | - |
dc.identifier.doi | 10.2337/diacare.26.6.1825 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02270 | - |
dc.contributor.localId | A03996 | - |
dc.relation.journalcode | J00721 | - |
dc.identifier.eissn | 1935-5548 | - |
dc.identifier.pmid | 12766117 | - |
dc.identifier.url | http://care.diabetesjournals.org/content/26/6/1825.long | - |
dc.subject.keyword | 12766117 | - |
dc.contributor.alternativeName | Ahn, Chul Woo | - |
dc.contributor.alternativeName | Cha, Bong Soo | - |
dc.contributor.affiliatedAuthor | Ahn, Chul Woo | - |
dc.contributor.affiliatedAuthor | Cha, Bong Soo | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 26 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1825 | - |
dc.citation.endPage | 1830 | - |
dc.identifier.bibliographicCitation | DIABETES CARE, Vol.26(6) : 1825-1830, 2003 | - |
dc.identifier.rimsid | 49274 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.