Cited 57 times in
The N Ratio Predicts Recurrence and Poor Prognosis in Patients With Node-Positive Early Gastric Cancer
DC Field | Value | Language |
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dc.contributor.author | 노성훈 | - |
dc.contributor.author | 송창수 | - |
dc.contributor.author | 정재호 | - |
dc.contributor.author | 최승호 | - |
dc.contributor.author | 형우진 | - |
dc.date.accessioned | 2015-06-10T12:19:42Z | - |
dc.date.available | 2015-06-10T12:19:42Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 1068-9265 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/109599 | - |
dc.description.abstract | BACKGROUND: The metastatic status of the regional node is the most significant prognostic factor for early gastric cancer (EGC). However, diverse prognoses are evident even among the same N classifications of the current tumor-node-metastasis system. The aim of this study was to evaluate the prognostic significance of the ratio of metastatic to retrieved lymph nodes (N ratio) in identifying a high-risk subgroup with node-positive EGC. METHODS: From a prospective database of 1264 EGC patients between 1987 and 1997, 156 (12.4%) were found to have histologically confirmed node metastasis. A number of prognostic factors, including the N ratio, were evaluated by univariate and multivariate analysis. RESULTS: The recurrence rate of node-positive EGC was 16.7% (n = 26). The overall 5-year survival rate of all patients was 84.0%. It was 26.9% and 95.4% in patients with and without recurrence, respectively (P < .0001; log-rank test). The cutoff value of the N ratio was set at .07. The 5-year survival rate of patients with an N ratio <.07 was 94.0%; this was significantly higher than the rate (72.6%) for those with a ratio >.07 (P < .0001; log-rank test). Both univariate and multivariate analysis identified the N ratio as the most significant predictive factor for recurrence and overall survival. Regarding stage migration, it shows superiority in comparison to the number-based N classification. CONCLUSIONS: The N ratio is a more effective and rational indicator for prognostic stratification of patients with lymph node-positive EGC than the current N classification of the tumor-node-metastasis system. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 377~385 | - |
dc.relation.isPartOf | ANNALS OF SURGICAL ONCOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Follow-Up Studies | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Lymphatic Metastasis* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neoplasm Recurrence, Local* | - |
dc.subject.MESH | Neoplasm Staging/methods* | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Stomach Neoplasms/pathology* | - |
dc.subject.MESH | Stomach Neoplasms/surgery | - |
dc.subject.MESH | Survival Analysis | - |
dc.title | The N Ratio Predicts Recurrence and Poor Prognosis in Patients With Node-Positive Early Gastric Cancer | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Surgery (외과학) | - |
dc.contributor.googleauthor | Jae-Ho Cheong | - |
dc.contributor.googleauthor | Woo Jin Hyung | - |
dc.contributor.googleauthor | Jian Guo Shen | - |
dc.contributor.googleauthor | Changsoo Song | - |
dc.contributor.googleauthor | Junuk Kim | - |
dc.contributor.googleauthor | Seung Ho Choi | - |
dc.contributor.googleauthor | Sung Hoon Noh | - |
dc.identifier.doi | 10.1245/ASO.2006.04.018 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A04102 | - |
dc.contributor.localId | A01281 | - |
dc.contributor.localId | A02070 | - |
dc.contributor.localId | A03717 | - |
dc.contributor.localId | A04382 | - |
dc.relation.journalcode | J00179 | - |
dc.identifier.eissn | 1534-4681 | - |
dc.identifier.pmid | 16450215 | - |
dc.identifier.url | http://link.springer.com/article/10.1245%2FASO.2006.04.018 | - |
dc.subject.keyword | Early gastric cancer | - |
dc.subject.keyword | Lymph node metastasis | - |
dc.subject.keyword | Metastatic lymph node ratio | - |
dc.subject.keyword | Prognosis Recurrence | - |
dc.contributor.alternativeName | Noh, Sung Hoon | - |
dc.contributor.alternativeName | Song, Chang Soo | - |
dc.contributor.alternativeName | Cheong, Jae Ho | - |
dc.contributor.alternativeName | Choi, Seung Ho | - |
dc.contributor.alternativeName | Hyung, Woo Jin | - |
dc.contributor.affiliatedAuthor | Choi, Seung Ho | - |
dc.contributor.affiliatedAuthor | Noh, Sung Hoon | - |
dc.contributor.affiliatedAuthor | Song, Chang Soo | - |
dc.contributor.affiliatedAuthor | Cheong, Jae Ho | - |
dc.contributor.affiliatedAuthor | Hyung, Woo Jin | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 13 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 377 | - |
dc.citation.endPage | 385 | - |
dc.identifier.bibliographicCitation | ANNALS OF SURGICAL ONCOLOGY, Vol.13(3) : 377-385, 2006 | - |
dc.identifier.rimsid | 38857 | - |
dc.type.rims | ART | - |
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