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새롭게 진단된 비만한 제2형 당뇨병 환자에서 Voglibose와 Glimepiride로 치료한 경우 복부 비만 및 대사적 이상에 미치는 영향에 대한 임상 비교
DC Field | Value | Language |
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dc.contributor.author | 김경래 | - |
dc.contributor.author | 안철우 | - |
dc.contributor.author | 이현철 | - |
dc.contributor.author | 임승길 | - |
dc.contributor.author | 차봉수 | - |
dc.date.accessioned | 2015-06-10T11:56:42Z | - |
dc.date.available | 2015-06-10T11:56:42Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 1226-4407 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/108905 | - |
dc.description.abstract | Background: To compare the effects of voglibose and glimepiride on adipose tissue and metabolic abnormalities in obese patients with newly diagnosed type 2 diabetes. Methods: Total of 40 obese patients with newly diagnosed type 2 diabetes (BMI > 25 ㎏/㎡) were included in this study. Study patients were randomized into voglibose group (n = 20) and glimepiride group (n = 20), where respective medication was administered for 12 weeks. We assessed the changes of biochemical parameters, body composition and serum adiponectin levels. Results: The voglibose treated group achieved a significant decrease in BMI, total body fat mass, and percent body fat (P < 0.05) after 12 weeks. A reduction in both subcutaneous and visceral abdominal adipose tissue area and VSR (visceral fat area/subcutaneous fat area) were noted only in the voglibose group (P < 0.05). Serum lipid profiles were similar between the two groups, except for the decrease in triglyceride levels, which were significant only in the voglibose group (P < 0.05). Serum adiponectin levels were increased only in the voglibose group (P < 0.05). Conclusions: In this study, voglibose showed to significantly decrease adipose tissue and improve adiponectin level. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 26~31 | - |
dc.language | Journal of Korean Society for the Study of Obesity | - |
dc.publisher | Journal of Korean Society for the Study of Obesity | - |
dc.relation.isPartOf | Journal of Korean Society for the Study of Obesity | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | 새롭게 진단된 비만한 제2형 당뇨병 환자에서 Voglibose와 Glimepiride로 치료한 경우 복부 비만 및 대사적 이상에 미치는 영향에 대한 임상 비교 | - |
dc.title.alternative | Effects of Voglibose and Glimepiride on Adipose Tissue and Metabolic Abnormalities in Patients with Newly Diagnosed Obese Type 2 Diabetes | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | 박종숙 | - |
dc.contributor.googleauthor | 김철식 | - |
dc.contributor.googleauthor | 김혜진 | - |
dc.contributor.googleauthor | 박진아 | - |
dc.contributor.googleauthor | 안철우 | - |
dc.contributor.googleauthor | 차봉수 | - |
dc.contributor.googleauthor | 임승길 | - |
dc.contributor.googleauthor | 김경래 | - |
dc.contributor.googleauthor | 이현철 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00294 | - |
dc.contributor.localId | A02270 | - |
dc.contributor.localId | A03301 | - |
dc.contributor.localId | A03375 | - |
dc.contributor.localId | A03996 | - |
dc.relation.journalcode | J01539 | - |
dc.identifier.eissn | 2234-7631 | - |
dc.subject.keyword | Adiponectin | - |
dc.subject.keyword | Adipose tissue | - |
dc.subject.keyword | Glimepiride | - |
dc.subject.keyword | Voglibose | - |
dc.contributor.alternativeName | Kim, Kyung Rae | - |
dc.contributor.alternativeName | Ahn, Chul Woo | - |
dc.contributor.alternativeName | Lee, Hyun Chul | - |
dc.contributor.alternativeName | Lim, Sung Kil | - |
dc.contributor.alternativeName | Cha, Bong Soo | - |
dc.contributor.affiliatedAuthor | Kim, Kyung Rae | - |
dc.contributor.affiliatedAuthor | Ahn, Chul Woo | - |
dc.contributor.affiliatedAuthor | Lee, Hyun Chul | - |
dc.contributor.affiliatedAuthor | Lim, Sung Kil | - |
dc.contributor.affiliatedAuthor | Cha, Bong Soo | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 15 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 26 | - |
dc.citation.endPage | 31 | - |
dc.identifier.bibliographicCitation | Journal of Korean Society for the Study of Obesity, Vol.15(1) : 26-31, 2006 | - |
dc.identifier.rimsid | 49955 | - |
dc.type.rims | ART | - |
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