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Regulator of G-protein Signaling (RGS) 단백질과 아편 신호 전달
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김기준 | - |
dc.date.accessioned | 2015-06-10T11:56:00Z | - |
dc.date.available | 2015-06-10T11:56:00Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 2005-9159 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/108884 | - |
dc.description.abstract | The regulators of the G protein signaling (RGS) proteins are responsible for the rapid acceleration of the GTPase-activity intrinsic to the heterotrimeric G protein alpha subunits. As GTPase-activating proteins (GAP), the RGS proteins negatively regulate the G-protein signals. Recently, the RGS proteins are known to be one of the important regulators of opioid signal transduction and the development of tolerance. The aim of this study was to review the recent discovery and understanding of the role of RGS proteins in opioid signaling and the development of tolerance. This information will be useful for medical personnel, particularly those involved in anesthesia and pain medicine, by helping them improve the effective use of opioids and develop new drugs that can prevent opioid tolerance. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | Korean | - |
dc.publisher | 대한통증학회 | - |
dc.relation.isPartOf | Korean Journal of Pain (대한통증학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Regulator of G-protein Signaling (RGS) 단백질과 아편 신호 전달 | - |
dc.title.alternative | RGS Proteins and Opioid Signaling | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Anesthesiology (마취통증의학) | - |
dc.contributor.googleauthor | 김경선 | - |
dc.contributor.googleauthor | Pamela Pierce Palmer | - |
dc.contributor.googleauthor | 김기준 | - |
dc.identifier.doi | 10.3344/kjp.2006.19.1.8 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00340 | - |
dc.relation.journalcode | J03702 | - |
dc.identifier.eissn | 2093-0569 | - |
dc.subject.keyword | opioid | - |
dc.subject.keyword | regulators of G protein signaling (RGS) protein | - |
dc.subject.keyword | tolerance. | - |
dc.contributor.alternativeName | Kim, Ki Jun | - |
dc.contributor.affiliatedAuthor | Kim, Ki Jun | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 19 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 8 | - |
dc.citation.endPage | 16 | - |
dc.identifier.bibliographicCitation | Korean Journal of Pain (대한통증학회지), Vol.19(1) : 8-16, 2006 | - |
dc.identifier.rimsid | 49940 | - |
dc.type.rims | ART | - |
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