Caudal midazolam does not affect sevoflurane requirements and recovery in pediatric day-case hernioplasty

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MeSH: Ambulatory Surgical Procedures ; Amides/administration & dosage ; Anesthesia Recovery Period ; Anesthesia, Caudal/methods* ; Anesthetics, Inhalation/administration & dosage* ; Anesthetics, Intravenous/administration & dosage* ; Anesthetics, Local/administration & dosage ; Child, Preschool ; Double-Blind Method ; Herniorrhaphy* ; Humans ; Male ; Methyl Ethers/administration & dosage* ; Midazolam/administration & dosage* ; Pain Measurement ; Prospective Studies ; Ropivacaine ; Sevoflurane ; Tidal Volume ; Treatment Outcome

Keywords: Ambulatory Surgical Procedures ; Amides/administration & dosage ; Anesthesia Recovery Period ; Anesthesia, Caudal/methods* ; Anesthetics, Inhalation/administration & dosage* ; Anesthetics, Intravenous/administration & dosage* ; Anesthetics, Local/administration & dosage ; Child, Preschool ; Double-Blind Method ; Herniorrhaphy* ; Humans ; Male ; Methyl Ethers/administration & dosage* ; Midazolam/administration & dosage* ; Pain Measurement ; Prospective Studies ; Ropivacaine ; Sevoflurane ; Tidal Volume ; Treatment Outcome

Abstract: BACKGROUND: This prospective, randomized, double-blind study aimed to determine whether caudal midazolam combined with ropivacaine affects anesthetic requirements, recovery profiles, and post-operative analgesia compared with ropivacaine alone in pediatric day-case hernioplasty.

METHODS: Sixty boys (2-5 years old) received caudal injections of 0.2% ropivacaine 1 ml/kg and epinephrine 1 : 200,000 with (RM group) or without (R group) 50 microg/kg of midazolam under sevoflurane anesthesia. The sevoflurane requirement was determined by adjusting to a bispectral index score=50.

RESULTS: Concentrations of end-tidal sevoflurane (ETsevo%) after induction were similar in both groups. After caudal block, ETsevo% before and after surgical stimuli did not show significant intra- or intergroup differences. Recovery characteristics, including post-operative sedations, were similar in both groups. Post-operative pain scores were significantly lower in the RM group than the R group.

CONCLUSIONS: Caudal midazolam (50 microg/kg) added to 2% ropivacaine did not influence sevoflurane requirement or recovery but improved post-operative analgesia compared with ropivacaine alone in pediatric day-case hernioplasty

Full Text: http://onlinelibrary.wiley.com/doi/10.1111/j.1399-6576.2008.01727.x/abstract

Appears in Collections:: 1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers

Yonsei Authors: Kil, Hae Keum(길혜금)
Park, Eun Young(박은영)
Shin, Seokyung(신서경) https://orcid.org/0000-0002-2641-0070
Cho, Jang Eun(조장은)
Hong, Jeong Yeon(홍정연)

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