Cited 9 times in
Analysis of anal sphincter preservation rate according to tumor level and neoadjuvant chemoradiotherapy in rectal cancer patients
DC Field | Value | Language |
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dc.contributor.author | 김남규 | - |
dc.contributor.author | 백승혁 | - |
dc.contributor.author | 손승국 | - |
dc.contributor.author | 이강영 | - |
dc.contributor.author | 조장환 | - |
dc.date.accessioned | 2015-05-19T16:58:31Z | - |
dc.date.available | 2015-05-19T16:58:31Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 1091-255X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/107291 | - |
dc.description.abstract | The anal sphincter preservation rate (ASPR) according to tumor level and neoadjuvant chemoradiotherpy (CRT) has not been fully evaluated. Therefore, the aim of this study was to evaluate the correlation between the tumor level, neoadjuvant CRT, and the ASPR in rectal cancer patients. We studied 544 patients (tumor level, 0-6 cm) who underwent curative resection for rectal cancer between 1991 and 2005. Patients were divided six into groups according to tumor level over 1-cm intervals, and the ASPR was evaluated in patients with and without neoadjuvant CRT according to tumor level. Sphincter preservation surgery was performed in 191 patients, and 86 patents underwent neoadjuvant CRT. The overall ASPR was 43.0% (37/86) in patients with neoadjuvant CRT and 33.6% (154/458) in patients without neoadjuvant CRT (P=0.094). In an analysis according to tumor level, the ASPR was 0.0 vs 0.0% in <or=1 cm, 0.0 vs 2.1% in 1<or=2 cm (P=0.589), 11.8 vs 16.8% in 2<or=3 cm (P=0.599), 55.6 vs 20.2% in 3<or=4 cm (P=0.001), 57.7 vs 45.9% in 4<or=5 cm (P=0.227), and 66.7 vs 69.5% in 5<or=6 cm (P=0.827). Neoadjuvant CRT did not increase the ASPR in tumor level within <or=6 cm. However, for the tumor level (3<or=4 cm), neoadjuvant CRT significantly increased the ASPR. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 176~182 | - |
dc.relation.isPartOf | JOURNAL OF GASTROINTESTINAL SURGERY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adenocarcinoma/drug therapy | - |
dc.subject.MESH | Adenocarcinoma/radiotherapy | - |
dc.subject.MESH | Adenocarcinoma/surgery | - |
dc.subject.MESH | Adenocarcinoma/therapy* | - |
dc.subject.MESH | Anal Canal/surgery* | - |
dc.subject.MESH | Antineoplastic Combined Chemotherapy Protocols/therapeutic use* | - |
dc.subject.MESH | Chemotherapy, Adjuvant/methods | - |
dc.subject.MESH | Colectomy/methods* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Fluorouracil/administration & dosage | - |
dc.subject.MESH | Follow-Up Studies | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Injections, Intravenous | - |
dc.subject.MESH | Leucovorin/administration & dosage | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neoadjuvant Therapy/methods* | - |
dc.subject.MESH | Radiotherapy, Adjuvant/methods | - |
dc.subject.MESH | Rectal Neoplasms/drug therapy | - |
dc.subject.MESH | Rectal Neoplasms/radiotherapy | - |
dc.subject.MESH | Rectal Neoplasms/surgery | - |
dc.subject.MESH | Rectal Neoplasms/therapy* | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Severity of Illness Index | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Analysis of anal sphincter preservation rate according to tumor level and neoadjuvant chemoradiotherapy in rectal cancer patients | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Surgery (외과학) | - |
dc.contributor.googleauthor | Seung Hyuk Baik | - |
dc.contributor.googleauthor | Nam Kyu Kim | - |
dc.contributor.googleauthor | Kang Young Lee | - |
dc.contributor.googleauthor | Seung Kook Sohn | - |
dc.contributor.googleauthor | Chang Hwan Cho | - |
dc.identifier.doi | 10.1007/s11605-007-0254-4 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00353 | - |
dc.contributor.localId | A01827 | - |
dc.contributor.localId | A01978 | - |
dc.contributor.localId | A02640 | - |
dc.contributor.localId | A03894 | - |
dc.relation.journalcode | J01418 | - |
dc.identifier.eissn | 1873-4626 | - |
dc.identifier.pmid | 17694418 | - |
dc.identifier.url | http://link.springer.com/article/10.1007%2Fs11605-007-0254-4 | - |
dc.subject.keyword | Anal sphincter preservation | - |
dc.subject.keyword | Neoadjuvant chemoradiotherpy | - |
dc.subject.keyword | Rectal cancer | - |
dc.contributor.alternativeName | Kim, Nam Kyu | - |
dc.contributor.alternativeName | Baik, Seung Hyuk | - |
dc.contributor.alternativeName | Sohn, Seung Kook | - |
dc.contributor.alternativeName | Lee, Kang Young | - |
dc.contributor.alternativeName | Cho, Chang Hwan | - |
dc.contributor.affiliatedAuthor | Kim, Nam Kyu | - |
dc.contributor.affiliatedAuthor | Baik, Seung Hyuk | - |
dc.contributor.affiliatedAuthor | Sohn, Seung Kook | - |
dc.contributor.affiliatedAuthor | Lee, Kang Young | - |
dc.contributor.affiliatedAuthor | Cho, Chang Hwan | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 12 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 176 | - |
dc.citation.endPage | 182 | - |
dc.identifier.bibliographicCitation | JOURNAL OF GASTROINTESTINAL SURGERY, Vol.12(1) : 176-182, 2008 | - |
dc.identifier.rimsid | 48263 | - |
dc.type.rims | ART | - |
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