Cited 8 times in
최근 4년 동안 전국의료기관에서 의뢰된 A형 간염바이러스 혈청 표지자 검사 결과에 대한 역학 분석
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 남정모 | - |
dc.date.accessioned | 2015-04-24T17:35:41Z | - |
dc.date.available | 2015-04-24T17:35:41Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 1598-6535 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/105697 | - |
dc.description.abstract | BACKGROUND: To establish effective preventive measures for hepatitis A virus (HAV) infection, a nationwide epidemiologic study on seroprevalence of anti-HAV and the disease prevalence is needed. The aim of this study was to analyze the recent sero-epidemiological changes of hepatitis A markers in Korea. METHODS: The results of 11,068 anti-HAV total and 32,360 anti-HAV IgM tests by electro-chemiluminescence immunoassay (ECLIA) that had been requested in recent four years (2005-2008) to a reference medical laboratory from 1,699 institutions nationwide were retrospectively analyzed according to the distribution of year, sex, and age groups. RESULTS: The overall positive rate of anti-HAV total was 62.8%. The overall positive rate of anti-HAV IgM was 11.0%, showing a significantly increasing trend by year: 7.7%, 10.9%, 8.9%, and 14.3% in 2005, 2006, 2007, and 2008, respectively (P<0.0001). The positive rate of anti-HAV IgM was higher in male than in female subjects (11.8% vs 10.0%, P<0.0001), and 81.8% (2,916/3,566) of the anti-HAV IgM positive results were observed in the age groups of 21-40 yr. The annual positive rates of anti-HAV total and anti-HAV IgM showed significantly decreasing and increasing trends, respectively, in the age groups of > or =21 yr. Conclusion: In accordance with a decreasing sero-positivity of anti-HAV total, the prevalence of acute hepatitis A virus infection has been considerably increased during the recent four years in the age groups of > or =21 yr. The results of this study could be used effectively as a basic data for establishing effective preventive measures for hepatitis A including vaccination in these susceptible age groups | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 563~569 | - |
dc.relation.isPartOf | KOREAN JOURNAL OF LABORATORY MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | 최근 4년 동안 전국의료기관에서 의뢰된 A형 간염바이러스 혈청 표지자 검사 결과에 대한 역학 분석 | - |
dc.title.alternative | An Epidemiological Analysis of Hepatitis A Virus Serologic Markers during the Recent Four Years in Korea. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Preventive Medicine (예방의학) | - |
dc.contributor.googleauthor | 이안나 | - |
dc.contributor.googleauthor | 임현선 | - |
dc.contributor.googleauthor | 남정모 | - |
dc.contributor.googleauthor | 송선미 | - |
dc.contributor.googleauthor | 윤혜령 | - |
dc.contributor.googleauthor | 이경률 | - |
dc.identifier.doi | 10.3343/kjlm.2009.29.6.563 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01264 | - |
dc.relation.journalcode | J02044 | - |
dc.subject.keyword | Hepatitis A | - |
dc.subject.keyword | Seroprevalence | - |
dc.subject.keyword | Anti-HAV total | - |
dc.subject.keyword | Anti-HAV IgM | - |
dc.contributor.alternativeName | Nam, Jung Mo | - |
dc.contributor.affiliatedAuthor | Nam, Jung Mo | - |
dc.citation.volume | 29 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 563 | - |
dc.citation.endPage | 569 | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL OF LABORATORY MEDICINE , Vol.29(6) : 563-569, 2009 | - |
dc.identifier.rimsid | 42675 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.