Cited 27 times in
Operative safety and oncologic outcomes of anal sphincter-preserving surgery with mesorectal excision for rectal cancer: 931 consecutive patients treated at a single institution
DC Field | Value | Language |
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dc.contributor.author | 이강영 | - |
dc.contributor.author | 김남규 | - |
dc.contributor.author | 김영완 | - |
dc.contributor.author | 조장환 | - |
dc.contributor.author | 민병소 | - |
dc.contributor.author | 손승국 | - |
dc.date.accessioned | 2015-04-24T16:31:59Z | - |
dc.date.available | 2015-04-24T16:31:59Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 1068-9265 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/103690 | - |
dc.description.abstract | BACKGROUND: This study was designed to evaluate the operative safety and long-term oncologic outcomes of sphincter-preserving surgery based on sharp mesorectal excision for rectal cancer. METHODS: Between January 1989 and June 2004, 931 patients underwent sphincter-preserving surgery based on sharp mesorectal excision. The operative safety and oncologic outcomes were assessed for the periods of 1989-1996 (n = 208) and 1997-2004 (n = 723). Total mesorectal excision (TME)-based sphincter-preserving surgery was performed during the period of 1989-1996. A multidisciplinary team approach and tailored mesorectal excision, which is the differential removal of the mesorectum, were our standard treatment for patients with rectal cancer during the period of 1997-2004. RESULTS: The use of preoperative chemoradiation (P < 0.001), ultralow anterior resection with coloanal anastomosis (P = 0.01), diverting stoma (P = 0.001), and <2 cm of a distal resection margin (P = 0.01) were more common during the period of 1997-2004. There were no differences between the two periods with regard to perioperative complications (P = 0.2), such as anastomosis leakage (2.4% vs. 3.6%). Cancer-specific survival rates (79.1% vs. 79.6%, P = 0.7) and local recurrence (8.4% vs. 8.6%, P = 0.99) did not differ significantly for the two periods. CONCLUSIONS: Based on sharp mesorectal excision, operative safety and oncologic outcomes were not compromised by technical advances in sphincter-preserving surgery using tailored mesorectal excision and a shortened distal margin. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 900~909 | - |
dc.relation.isPartOf | ANNALS OF SURGICAL ONCOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adenocarcinoma/surgery* | - |
dc.subject.MESH | Adenocarcinoma/therapy | - |
dc.subject.MESH | Anal Canal | - |
dc.subject.MESH | Chemotherapy, Adjuvant | - |
dc.subject.MESH | Colectomy/methods* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neoadjuvant Therapy | - |
dc.subject.MESH | Radiotherapy, Adjuvant | - |
dc.subject.MESH | Rectal Neoplasms/surgery* | - |
dc.subject.MESH | Rectal Neoplasms/therapy | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Operative safety and oncologic outcomes of anal sphincter-preserving surgery with mesorectal excision for rectal cancer: 931 consecutive patients treated at a single institution | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Surgery (외과학) | - |
dc.contributor.googleauthor | Nam-Kyu Kim | - |
dc.contributor.googleauthor | Young-Wan Kim | - |
dc.contributor.googleauthor | Byung-Soh Min | - |
dc.contributor.googleauthor | Kang-Young Lee | - |
dc.contributor.googleauthor | Seung-Kook Sohn | - |
dc.contributor.googleauthor | Chang-Hwan Cho | - |
dc.identifier.doi | 10.1245/s10434-009-0340-9 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02640 | - |
dc.contributor.localId | A00353 | - |
dc.contributor.localId | A00720 | - |
dc.contributor.localId | A03894 | - |
dc.contributor.localId | A01402 | - |
dc.contributor.localId | A01978 | - |
dc.relation.journalcode | J00179 | - |
dc.identifier.eissn | 1534-4681 | - |
dc.identifier.pmid | 19198951 | - |
dc.identifier.url | http://link.springer.com/article/10.1245%2Fs10434-009-0340-9 | - |
dc.contributor.alternativeName | Lee, Kang Young | - |
dc.contributor.alternativeName | Kim, Nam Kyu | - |
dc.contributor.alternativeName | Kim, Young Wan | - |
dc.contributor.alternativeName | Cho, Chang Hwan | - |
dc.contributor.alternativeName | Min, Byung Soh | - |
dc.contributor.alternativeName | Sohn, Seung Kook | - |
dc.contributor.affiliatedAuthor | Lee, Kang Young | - |
dc.contributor.affiliatedAuthor | Kim, Nam Kyu | - |
dc.contributor.affiliatedAuthor | Kim, Young Wan | - |
dc.contributor.affiliatedAuthor | Cho, Chang Hwan | - |
dc.contributor.affiliatedAuthor | Min, Byung Soh | - |
dc.contributor.affiliatedAuthor | Sohn, Seung Kook | - |
dc.citation.volume | 16 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 900 | - |
dc.citation.endPage | 909 | - |
dc.identifier.bibliographicCitation | ANNALS OF SURGICAL ONCOLOGY, Vol.16(4) : 900-909, 2009 | - |
dc.identifier.rimsid | 36630 | - |
dc.type.rims | ART | - |
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