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AMS 700CX/CXM inflatable penile prosthesis has high mechanical reliability at long-term follow-up

Authors
 Dong Suk Kim  ;  Kwang Mo Yang  ;  Hyun Jin Chung  ;  Hyun Min Choi  ;  Young Deuk Choi  ;  Hyung Ki Choi 
Citation
 JOURNAL OF SEXUAL MEDICINE, Vol.7(7) : 2602-2607, 2010 
Journal Title
JOURNAL OF SEXUAL MEDICINE
ISSN
 1743-6095 
Issue Date
2010
MeSH
Adult ; Aged ; Aged, 80 and over ; Humans ; Impotence, Vasculogenic/surgery ; Impotence, Vasculogenic/therapy* ; Kaplan-Meier Estimate ; Korea ; Male ; Middle Aged ; Patient Satisfaction ; Penile Prosthesis* ; Postoperative Complications ; Prosthesis Design/statistics & numerical data* ; Prosthesis Failure ; Retrospective Studies ; Surveys and Questionnaires ; Time Factors ; Young Adult
Keywords
Penile Implantation ; Penile Prosthesis ; Erectile Dysfunction ; Survival
Abstract
INTRODUCTION: AMS 700CX/CXM inflatable penile prosthesis is increasingly applied for the treatment of erectile dysfunction (ED). However, there are a few long-term survival data of the inflatable penile prosthesis (IPP) over 10 years.

AIM: To determine the long-term mechanical reliability of AMS 700CX/CXM inflatable penile prosthesis in patients with ED.

METHODS: A total of 438 consecutive patients with ED received implantation of an AMS 700CX/CXM penile prosthesis at our institution from January 1991 to April 2009. In 397 patients (90.7%), the medical records were available and current status of penile prosthesis could be obtained by a direct telephone interview. The overall and mechanical survival rates of penile prosthesis were evaluated using Kaplan-Meier method.

MAIN OUTCOME MEASURES: Assessing the mechanical and overall survival rates of the AMS 700CX/CXM penile prosthesis using Kaplan-Meier analysis, and looking for clinical factors related to survival of the CX/CXM using log-rank test.

RESULTS: Mean age of 397 patients was 63.1 years (range, 24-93) and follow-up duration was 113 months (range 1-219). Eighty-two patients (20.6%) experienced mechanical failure at a median follow-up of 82 months. Mechanical survival rate of the penile prosthesis was 97.6%, 93.2% and 78.2% at 3, 5, and 10 years after implantation, respectively. 12 patients (3.0%) experienced nonmechanical failure including infections, tissue erosion resulting in cylinder protrusion at the meatus and chronic discomfort. Overall survival rate of the penile prosthesis was 95.0%, 91.0% and 75.5% at 3, 5, and 10 years after implantation, respectively. Patients with neurogenic cause for ED showed lower median overall survival of penile prosthesis compared with patients with non-neurogenic cause. Patient age, obesity, and diabetes mellitus had no association with overall survival of penile prosthesis after implantation.

CONCLUSIONS: The AMS 700CX/CXM could be accepted and applied in more patients as a reliable treatment alternative of ED.
Full Text
http://onlinelibrary.wiley.com/doi/10.1111/j.1743-6109.2010.01801.x/abstract
DOI
10.1111/j.1743-6109.2010.01801.x
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Dong Suk(김동석)
Jung, Hyun Jin(정현진)
Choi, Young Deuk(최영득) ORCID logo https://orcid.org/0000-0002-8545-5797
Choi, Hyung Ki(최형기)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/101909
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