Cited 0 times in
AFM 캔틸레버를 이용한 i-motif DNA의 구조 변화에 미치는 화학적 환경에 대한 연구
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 양재문 | - |
dc.date.accessioned | 2015-04-23T16:44:44Z | - |
dc.date.available | 2015-04-23T16:44:44Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 1225-5475 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/101146 | - |
dc.description.abstract | Three-dimensional(3D) structure of specific DNA can be changed between two conformations under an external environmental transition such as pH and salt concentration variations. We have experimentally observed the conformational transitions of i-motif DNA using AFM cantilever bioassay. It is shown that pH change of a solvent induces the bending defleciton change of a cantilever functionalized by i-motif DNA. This indicates that cantilever bioassay enables the label-free detection of DNA structural changes upon pH change. It is implied that cantilever bioassay can be a de novo route to quantitatively understand the conformational transitions of biological molecules under environmental changes | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 214~220 | - |
dc.relation.isPartOf | Journal of Sensor Science and Technology (센서학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | AFM 캔틸레버를 이용한 i-motif DNA의 구조 변화에 미치는 화학적 환경에 대한 연구 | - |
dc.title.alternative | Study on the chemical environment for conformational change of i-motif DNA by atomic force microscopy cantilever | - |
dc.type | Article | - |
dc.contributor.college | Researcher Institutes (부설 연구소) | - |
dc.contributor.department | Yonsei Integrative Research Institute for Cerebral & Cardiovascular Disease (뇌심혈관질환융합연구사업단) | - |
dc.contributor.googleauthor | 정휘헌 | - |
dc.contributor.googleauthor | 박진성 | - |
dc.contributor.googleauthor | 양재문 | - |
dc.contributor.googleauthor | 이상우 | - |
dc.contributor.googleauthor | 엄길호 | - |
dc.contributor.googleauthor | 권태윤 | - |
dc.contributor.googleauthor | 윤대성 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02315 | - |
dc.relation.journalcode | J01745 | - |
dc.subject.keyword | atomic force microscopy | - |
dc.subject.keyword | conformational change | - |
dc.subject.keyword | cantilever | - |
dc.subject.keyword | i-motif | - |
dc.subject.keyword | monovalent cation | - |
dc.contributor.alternativeName | Yang, Jae Moon | - |
dc.contributor.affiliatedAuthor | Yang, Jae Moon | - |
dc.citation.volume | 19 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 214 | - |
dc.citation.endPage | 220 | - |
dc.identifier.bibliographicCitation | Journal of Sensor Science and Technology (센서학회지), Vol.19(3) : 214-220, 2010 | - |
dc.identifier.rimsid | 52097 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.