Cited 13 times in
Titrated propofol induction vs. continuous infusion in children undergoing magnetic resonance imaging
DC Field | Value | Language |
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dc.contributor.author | 길혜금 | - |
dc.contributor.author | 김원옥 | - |
dc.contributor.author | 조장은 | - |
dc.contributor.author | 최은경 | - |
dc.date.accessioned | 2015-04-23T16:30:23Z | - |
dc.date.available | 2015-04-23T16:30:23Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0001-5172 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/100707 | - |
dc.description.abstract | BACKGROUND: Propofol is the popular intravenous (i.v.) anaesthetic for paediatric sedation because of its rapid onset and recovery. We compared the efficacy and safety of a single dose and conventional infusion of propofol for sedation in children who underwent magnetic resonance imaging (MRI). METHODS: This was a double-blind, randomized-controlled study. One hundred and sixty children were assigned to group I (single dose) or II (infusion). Sedation was induced with i.v. propofol 2 mg/kg, and supplemental doses of propofol 0.5 mg/kg were administered until adequate sedation was achieved. After the induction of sedation, we treated patients with a continuous infusion of normal saline at a rate of 0.3 ml/kg/h in group I and the same volume of propofol in group II. In case of inadequate sedation, additional propofol 0.5 mg/kg was administered and the infusion rate was increased by 0.05 ml/kg/h. Induction time, sedation time, recovery time, additional sedation and adverse events were recorded. RESULTS: Recovery time was significantly shorter in group I compared with group II [0 (0-3) vs. 1 (0-3), respectively, P<0.001]. Group I (single dose) had significantly more patients with recovery time 0 compared with group II (infusion) (65/80 vs. 36/80, respectively, P<0.001). Induction and sedation times were not significantly different between groups. There was no significant difference in the frequency of additional sedation and adverse events between groups. CONCLUSION: A single dose of propofol without a continuous infusion can provide appropriate sedation in children undergoing MRI for <30 min. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 453~457 | - |
dc.relation.isPartOf | ACTA ANAESTHESIOLOGICA SCANDINAVICA | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Anesthesia Recovery Period | - |
dc.subject.MESH | Anesthetics, Intravenous*/administration & dosage | - |
dc.subject.MESH | Anesthetics, Intravenous*/adverse effects | - |
dc.subject.MESH | Blood Pressure/drug effects | - |
dc.subject.MESH | Carbon Dioxide/blood | - |
dc.subject.MESH | Child | - |
dc.subject.MESH | Child, Preschool | - |
dc.subject.MESH | Conscious Sedation/methods* | - |
dc.subject.MESH | Double-Blind Method | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Heart Rate/drug effects | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Infant | - |
dc.subject.MESH | Infusions, Intravenous | - |
dc.subject.MESH | Magnetic Resonance Imaging/methods* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Oxygen/blood | - |
dc.subject.MESH | Patient Satisfaction | - |
dc.subject.MESH | Propofol*/administration & dosage | - |
dc.subject.MESH | Propofol*/adverse effects | - |
dc.subject.MESH | Respiratory Mechanics/drug effects | - |
dc.subject.MESH | Sample Size | - |
dc.title | Titrated propofol induction vs. continuous infusion in children undergoing magnetic resonance imaging | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Anesthesiology (마취통증의학) | - |
dc.contributor.googleauthor | J. E. CHO | - |
dc.contributor.googleauthor | W. O. KIM | - |
dc.contributor.googleauthor | D. J. CHANG | - |
dc.contributor.googleauthor | E. M. CHOI | - |
dc.contributor.googleauthor | S. Y. OH | - |
dc.contributor.googleauthor | H. K. KIL | - |
dc.identifier.doi | 10.1111/j.1399-6576.2009.02169.x | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00283 | - |
dc.contributor.localId | A00766 | - |
dc.contributor.localId | A03893 | - |
dc.contributor.localId | A04146 | - |
dc.relation.journalcode | J00006 | - |
dc.identifier.eissn | 1399-6576 | - |
dc.identifier.pmid | 19930245 | - |
dc.identifier.url | http://onlinelibrary.wiley.com/doi/10.1111/j.1399-6576.2009.02169.x/abstract | - |
dc.contributor.alternativeName | Kil, Hae Keum | - |
dc.contributor.alternativeName | Kim, Won Oak | - |
dc.contributor.alternativeName | Cho, Jang Eun | - |
dc.contributor.alternativeName | Choi, Eun Kyeong | - |
dc.contributor.affiliatedAuthor | Kil, Hae Keum | - |
dc.contributor.affiliatedAuthor | Kim, Won Oak | - |
dc.contributor.affiliatedAuthor | Cho, Jang Eun | - |
dc.contributor.affiliatedAuthor | Choi, Eun Kyeong | - |
dc.citation.volume | 54 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 453 | - |
dc.citation.endPage | 457 | - |
dc.identifier.bibliographicCitation | ACTA ANAESTHESIOLOGICA SCANDINAVICA, Vol.54(4) : 453-457, 2010 | - |
dc.identifier.rimsid | 37761 | - |
dc.type.rims | ART | - |
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