Cited 21 times in
Programmed death-1 (PD-1) gene polymorphisms lodged in the genetic predispositions of Kawasaki Disease
DC Field | Value | Language |
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dc.contributor.author | 김동수 | - |
dc.contributor.author | 신전수 | - |
dc.contributor.author | 유병원 | - |
dc.date.accessioned | 2015-04-23T16:25:44Z | - |
dc.date.available | 2015-04-23T16:25:44Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0340-6199 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/100564 | - |
dc.description.abstract | The purpose of this study is to investigate the association of programmed death-1 gene (PD-1) polymorphisms with genetic predispositions to Kawasaki disease (KD). A total of 73 patients with KD and 100 healthy controls were enrolled from 2007 to 2008. Two single nucleotide polymorphisms of the PD-1 gene, rs41386349 and rs2227981, were analyzed. Higher T allele frequency of rs41386349 was found in the patient group than the control group (p = 0.007, odds ratio (OR) = 1.9, 95% CI = 1.2-2.9). PD-1 rs2227981 polymorphism was not significant in patients with KD comparing with the control group (p = 0.4, OR = 1.2 (0.8-1.9)). Furthermore, no difference of PD-1 polymorphisms between patients with coronary artery dilatation (CAD) and those without CAD was found. Our data support the possibility that PD-1 gene polymorphism may be related with the genetic susceptibility of KD in Korean population. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 181~185 | - |
dc.relation.isPartOf | EUROPEAN JOURNAL OF PEDIATRICS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Antigens, CD/blood | - |
dc.subject.MESH | Antigens, CD/genetics* | - |
dc.subject.MESH | Apoptosis Regulatory Proteins/blood | - |
dc.subject.MESH | Apoptosis Regulatory Proteins/genetics* | - |
dc.subject.MESH | Child | - |
dc.subject.MESH | Child, Preschool | - |
dc.subject.MESH | DNA/genetics* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Genetic Predisposition to Disease/genetics* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Incidence | - |
dc.subject.MESH | Lymphocyte Activation | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Mucocutaneous Lymph Node Syndrome/blood | - |
dc.subject.MESH | Mucocutaneous Lymph Node Syndrome/epidemiology | - |
dc.subject.MESH | Mucocutaneous Lymph Node Syndrome/genetics* | - |
dc.subject.MESH | Odds Ratio | - |
dc.subject.MESH | Polymerase Chain Reaction | - |
dc.subject.MESH | Polymorphism, Genetic* | - |
dc.subject.MESH | Programmed Cell Death 1 Receptor | - |
dc.subject.MESH | Republic of Korea/epidemiology | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Young Adult | - |
dc.title | Programmed death-1 (PD-1) gene polymorphisms lodged in the genetic predispositions of Kawasaki Disease | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pediatrics (소아과학) | - |
dc.contributor.googleauthor | Jin-Kyong Chun | - |
dc.contributor.googleauthor | Dong Won Kang | - |
dc.contributor.googleauthor | Byung Won Yoo | - |
dc.contributor.googleauthor | Jeon-Soo Shin | - |
dc.contributor.googleauthor | Dong Soo Kim | - |
dc.identifier.doi | 10.1007/s00431-009-1002-4 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02144 | - |
dc.contributor.localId | A02468 | - |
dc.contributor.localId | A00405 | - |
dc.relation.journalcode | J00839 | - |
dc.identifier.eissn | 1432-1076 | - |
dc.identifier.pmid | 19468750 | - |
dc.identifier.url | http://link.springer.com/article/10.1007%2Fs00431-009-1002-4 | - |
dc.subject.keyword | Programmed death-1 gene | - |
dc.subject.keyword | Kawasaki disease | - |
dc.subject.keyword | Vasculitis | - |
dc.subject.keyword | Single nucleotide polymorphism | - |
dc.contributor.alternativeName | Kim, Dong Soo | - |
dc.contributor.alternativeName | Shin, Jeon Soo | - |
dc.contributor.alternativeName | Yoo, Byung Won | - |
dc.contributor.affiliatedAuthor | Shin, Jeon Soo | - |
dc.contributor.affiliatedAuthor | Yoo, Byung Won | - |
dc.contributor.affiliatedAuthor | Kim, Dong Soo | - |
dc.citation.volume | 169 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 181 | - |
dc.citation.endPage | 185 | - |
dc.identifier.bibliographicCitation | EUROPEAN JOURNAL OF PEDIATRICS, Vol.169(2) : 181-185, 2010 | - |
dc.identifier.rimsid | 36569 | - |
dc.type.rims | ART | - |
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